Exploratory Analyses of Cerebral Gray Matter Volumes After Out-of-Hospital Cardiac Arrest in Good Outcome Survivors

Frontiers in Psychology

article

Aziza Byron-Alhassan¹  Heather E. Tulloch¹  Barbara Collins¹  Bonnie Quinlan¹  Zhuo Fang²  Santanu Chakraborty³  Michel Le May³  Lloyd Duchesne³  Andra M. Smith² 

[1] Department of Cardiac Prevention and Rehabilitation, University of Ottawa Heart Institute;School of Psychology, University of Ottawa;Faculty of Medicine, University of Ottawa;Department of Medical Imaging, The Ottawa Hospital

关键词: out-of-hospital cardiac arrest;    gray matter volume;    cognition;    myocardial infarction;    magnetic resonance imaging;   

DOI  :  10.3389/fpsyg.2020.00856

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Background Survival rates of cardiac arrest have increased over recent years, however, survivors may still be left with significant morbidity and functional impairment. A primary concern in cardiac arrest survivors is the effect of prolonged hypoxia/ischemia on the brain. The objectives of the present study were threefold: (1) to explore the effect of cardiac arrest on brain gray matter volumes (GMV) in “good outcome” survivors of out-of-hospital cardiac arrest (OHCA), (2) to examine the relationship between GMV, cognitive functioning and arrest factors, and (3) to explore whether OHCA patients differ from a group of patients with myocardial infarction (MI) uncomplicated by cardiac arrest and a group of healthy controls in terms of GMV.

【 授权许可】

CC BY