Commentary: Microbial Resistance Movements: An Overview of Global Public Health Threats Posed by Antimicrobial Resistance, and How Best to Counter

Frontiers in Public Health

article

Mohammed S. Razzaque¹ 

[1] Department of Pathology, Lake Erie College of Osteopathic Medicine, United States

关键词: microbial resistance;    antibiotics;    Public Health;    antimicrobial stewardship;    global healh;   

DOI  :  10.3389/fpubh.2020.629120

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

“Superbugs” are the antimicrobial-resistant microorganisms. Bacteria, viruses, fungi, and parasitesacquire the ability to evade the antimicrobial drug effects, not only to survive but also, in some cases,become more virulent. As such, the existing antimicrobial drugs are no longer effective and useful intreating the infections (used to be treatable). Superbug-induced infections are the major worldwidehealth concern with higher human mortality and an increased financial burden on society. Theunderlying mechanism of the evolvement of drug-sensitive to drug-resistant microorganisms isan extremely complex phenomenon. It is partly related to microorganism’s unique ability tomodify their genetic structures and biochemical functionality to survive and keep growing evenin the presence of antimicrobial drugs. Since there are multiple factors involved in developingantimicrobial drug resistance, it cannot be reversed by adopting a single prevention strategy. Ofimportance, certain bacterium may not require antimicrobial drug exposure to develop resistance,as surrounding environmental exposure can facilitate the resistance.

【 授权许可】

CC BY