Systematic Review of Functional Mapping and Cortical Reorganization in the Setting of Arteriovenous Malformations, Redefining Anatomical Eloquence

Frontiers in Surgery

article

Sauson Soldozy¹  M. Yashar S. Kalani¹  Daniel K. Akyeampong¹  David L. Barquin¹  Pedro Norat¹  Kaan Yağmurlu¹  Jennifer D. Sokolowski¹  Khadijeh A. Sharifi¹  Petr Tvrdik¹  Min S. Park¹ 

[1] Department of Neurological Surgery, University of Virginia Health System, United States

关键词: arteriovenous malformation (AVM);    functional reorganization;    brain mapping;    neurosurgical outcomes;    fMRI;    TMS (transcranial magnetic stimulation);    MEG (magnetoencephalography);    MSI (magnetic source imaging);   

DOI  :  10.3389/fsurg.2020.514247

学科分类：社会科学、人文和艺术（综合）

来源: Frontiers

【 摘 要 】

Objective: The goal of this study was to systematically review functional mapping and reorganization that takes place in the setting of arteriovenous malformations (AVMs) and its potential impact on grading and surgical decision making. Methods: A systematic literature review was performed using the PubMed database for studies published between 1986 and 2019. Studies assessing brain mapping and functional reorganization in AVMs were included. Results: Of the total 84 articles identified in the original literature search, 12 studies were ultimately selected. This includes studies evaluating the impact of cortical reorganization on patient outcomes and factors impacting and triggering cortical reorganization in AVM. Conclusion: These studies demonstrate the utility of preoperative brain mapping and acknowledgment of functional reorganization in the setting of AVMs. While these findings led to alterations in Spetzler–Martin grading and subsequent surgical decision making, it remains unclear the clinical utility of this information when assessing patient outcomes. While promising, more research is required before recommendations can be made regarding functional brain mapping and cortical reorganization with respect to AVM surgery involving eloquent brain tissue.

【 授权许可】

CC BY