Isolation of antifungal-resistant yeasts from bulk milk in Japan

The Journal of Veterinary Medical Science

article

Ryoka MIYAKE¹  Takakaki ITO²  Hiroshi KAMATA¹  Rui KANO¹ 

[1] Nihon University College of Bioresource Sciences;Veterinary Hospital Aichi P.F.A.M.A.A.

关键词: antifungal resistance;    bulk milk;    Candida;    cow;    susceptibility testing;   

DOI  :  10.1292/jvms.21-0023

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

We isolated ascomycetous yeasts including Candida species, that originally belonged to the genus Candida, from bulk milk in the Aichi area of Japan, and determined the minimum inhibitory concentrations (MICs) of antifungal drugs on these isolates by conducting E-tests. We isolated 7 human pathogenic species (14 isolates) from 14 bulk milk samples: 5 Candida species of yeasts, and 2 Candida -related species. Two isolates of C. albicans and C. inconspicua were resistant to fluconazole (MIC >32 mg/l). One isolate of C. krusei was resistant to both azoles (fluconazole: >256 mg/ml and itraconazole: 4 mg/l). One isolate of C. catenulata might be resistant to amphotericin B (>32 mg/l).

【 授权许可】

Unknown