Mediastinal basaloid carcinoma arising from thymic cysts in two dogs

The Journal of Veterinary Medical Science

article

Yuto SANO¹  Kanae SEKI¹  Kenjirou MIYOSHI²  Toshikazu SAKAI²  Tsuyoshi KADOSAWA²  Kazuya MATSUDA¹ 

[1] Department of Veterinary Pathology, School of Veterinary Medicine, Rakuno Gakuen University;Department of Small Animal Clinical Sciences, School of Veterinary Medicine, Rakuno Gakuen University

关键词: basaloid carcinoma;    dog;    mediastinum;    thymic branchial cyst;    thymic cyst;   

DOI  :  10.1292/jvms.20-0518

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

Mediastinal masses in dogs were diagnosed as basaloid carcinoma associated with multiple thymic cysts (MTCs). The masses were composed of MTCs and proliferating intracystic neoplastic basaloid cells, which immunohistochemically diffusely expressed p63 and cytokeratin 19. A gradual transition from the basal cell layers lining the cysts walls to the neoplastic cells was seen, and it was indicated that the neoplastic cells had originated from the basal cell layers of the cysts. To the best of our knowledge, this is the first report of basaloid carcinoma occurring in the mediastinal cavity in dogs. Although these tumors were demonstrated to be rare origins, basaloid carcinoma should be included in the differential diagnoses for canine mediastinal tumors.

【 授权许可】

Unknown