Severe calcification of systemic blood vessel walls caused by continuous hypercalcemia in a cat with congenital hypothyroidism

The Journal of Veterinary Medical Science

article

Yusuke TANAKA¹  Michio OOIKE²  Kenichi WATANABE¹  Noriyuki HORIUCHI¹  Yoshiyasu KOBAYASHI¹ 

[1] Department of Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine;Ooike Animal Hospital

关键词: calcification;    congenital hypothyroidism;    hypercalcemia;    hyperparathyroidism;   

DOI  :  10.1292/jvms.20-0391

学科分类：兽医学

来源: Japanese Society of Veterinary Science

【 摘 要 】

A 97-day-old male Japanese domestic cat was diagnosed as congenital hypothyroidism. During the treatment, continuous hypercalcemia was detected. Although fluid therapy was performed, the cat died at the age of 1785 days. At autopsy, both parathyroid glands were enlarged, and elastic arterial walls were increased in thickness and hardness. Histopathological examination revealed hyperplasia of both parathyroid glands and interstitial fibrosis of bilateral kidneys. Severe calcification of the tunica media and tunica externa in systemic elastic and muscular arteries were also observed. These calcifications were considered to be due to renal secondary hyperparathyroidism. In the present case, hypothyroidism might have caused hyperparathyroidism through renal failure. In veterinary medicine, this is the first reported case of hypothyroidism accompanied with hyperparathyroidism.

【 授权许可】

Unknown