Risk Factors of Clonorchis sinensis Human Infections in Endemic Areas, Haman-Gun, Republic of Korea: A Case-Control Study

The journal of physiological sciences

article

Sang-Eun Lee¹  Hee-Eun Shin¹  Myoung-Ro Lee¹  Yang-Hee Kim²  Shin-Hyeong Cho¹  Jung-Won Ju¹ 

[1] Division of Vectors and Parasitic Diseases;Haman-gun Public Health Center

关键词: Clonorchis sinensis;    risk factor;    freshwater fish;    fish-borne trematode;    Haman-gun;    Korea;   

DOI  :  10.3347/kjp.2020.58.6.647

来源: Springer

【 摘 要 】

Clonorchis sinensis is the most common fish-borne intestinal parasite in Korea. The aim of the present investigation was to survey the status of C. sinensis infection and analyze associated risk factors in residents of Haman-gun, Gyeongsangnam-do. A total of 5,114 residents from 10 administrative towns/villages voluntarily agreed to participate in the study, which comprised fecal examination, a questionnaire survey for risk factors, ultrasonography, and enzymelinked immunosorbent assay for cancer biomarker detection in the blood. We detected C. sinensis eggs in 5.3% of the subjects. By region, Gunbuk-myeon had the highest number of residents with C. sinensis eggs. The infection rate and intensity were higher in male than in female residents. Based on the risk factor questionnaire, infection was highly associated with drinking, a history of C. sinensis infection, and the practice of eating of raw freshwater fish. Extension of the bile duct, infection intensity, and cancer biomarker detection significantly correlated with the presence of eggs in the study population. In conclusion, the development of feasible, long-term control policies and strategies for the elimination of C. sinensis in Korea is still required.

【 授权许可】

Unknown