A case series of post COVID-19 mucormycosis—a neurological prospective

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

Tamer Roushdy¹  Eman Hamid¹ 

[1] Neurology Department, Faculty of Medicine, Ain Shams University, PO 11591, 38 Abbasia, Cairo, Egypt;

关键词: Coronavirus;    COVID-19;    Mucormycosis;    Orbital cellulitis;    Orbital apex syndrome;    Cavernous sinus thrombosis;   

DOI  :  10.1186/s41983-021-00355-8

来源: Springer

【 摘 要 】

BackgroundDirect neurological manifestations of coronavirus disease whether peripheral or central are reported worldwide. Yet, along the 3rd wave of the pandemic especially in India, an associated angioinvasive opportunistic infection with mucormycosis in COVID-19 cases is emerging.Case presentationThe current case series which represents 4 patients with mucormycosis post COVID-19 is one of a few if not the first case series that discusses post COVID-19 mucormycosis from a neurological prospective in a tertiary hospital in Egypt.All cases but one presented with total ophthalmoplegia, and only one was diagnosed as a cavernous sinus thrombosis; meanwhile, orbital cellulitis and orbital apex syndrome were responsible of ophthalmoplegia in two cases.Mortality reached 25%, and the case that died suffered cutaneous as well as rhino-cerebral type with a delayed presentation to hospital.ConclusionA rare but fatal fungal infection is ought to be nowadays kept in mind in COVID-19 active cases as well as in recovered COVID-19 patients, especially those who have comorbid medical conditions as uncontrolled diabetes and who were treated with large doses of corticosteroids.

【 授权许可】

CC BY