RETRACTED ARTICLE: High failure rate after Beta-tricalcium phosphate grafting for the treatment of femoral head osteonecrosis: a retrospective analysis

BMC Musculoskeletal Disorders

Pei Liu¹  Jian-lei Guan¹  Xiao-hong Mu²  Qi-dong Zhang³  Zhao-hui Liu³  Wan-shou Guo³  Wei-guo Wang³  Hua-chen Yu⁴ 

[1] Beijing University of Chinese Medicine, Yinghuadong Road, Chaoyang District, Beijing, China;Department Orthopedics 4, Beijing University of Chinese Medicine, Dongzhimen Hospital, Beijing, China;Department of Orthopaedic Surgery, Beijing Key Lab Immune-Mediated Inflammatory Diseases, China-Japan Friendship Hospital, No. 2, Yinghuadong Road, Chaoyang District, 100029, Beijing, China;Graduate School of Peking Union Medical College, Beijing, China;

关键词: Osteonecrosis of the femoral head;    Beta-tricalcium phosphate;    Head-preserving surgery;   

DOI  :  10.1186/s12891-020-03291-5

来源: Springer

【 摘 要 】

BackgroundNon-vascularized bone grafting is a promising head-preserving technique for younger patients diagnosed as non-traumatic osteonecrosis of the femoral head (NONFH). Among the various types of bone grafting techniques, “light-bulb” procedure grafting with synthetic bone substitute is an attractive option. We aimed to assess the effectiveness of using beta-tricalcium phosphate (β-TCP) for the treatment of pre-collapse and early post-collapse lesions NONFH.MethodsFrom April 2010 to June 2014, 33 patients (47 hips) with NONFH were treated using the afore-mentioned technique. The clinical and radiological outcomes were recorded and compared statistically between pre- and post-operation. Harris hip score (HHS) was used to evaluate the clinical results, and Association Research Circulation Osseous (ARCO) stage was applied to assess the radiological outcomes.ResultsThe 5-years survival rate of using β-TCP grafting was accounting for 25.5%. HHS was decreased from 78.47 to 52.87 points, and a very significant worsening of radiological results were revealed (P <  0.05). Two hips collapsed more than 2 mm were awaiting for THA, and 33 of the 47 hips had converted to THAs in an average time to failure of 24.24 months postoperatively. Meanwhile, only 4 hips survived without collapse, and 8 hips collapsed less than 2 mm. After surgery, the time onset of head collapse was 3.65 months on average, and the first conversion to THA was performed at 5 months postoperative.ConclusionsOur results suggest that “light-bulb” procedure grafting with β-TCP sticks presented with a high failure rate in the early postoperative period. It is not proposed for the treatment of pre-collapse and early post-collapse lesions NONFH.

【 授权许可】

CC BY