Ethmoid glomangioma and oncogenic osteomalacia: a case report

Journal of Medical Case Reports

Catarina B. D’Alva¹  Camila R. Muniz²  Gabriela A. M. Bezerra²  Viviane C. da Silva²  André A. A. Nunes²  Priscilla M. F. Aguiar³  Gunter Gerson³ 

[1] Department of Endocrinology, Walter Cantídio University Hospital of Ceará Federal University, Fortaleza, Brazil;Department of Otorhinolaryngology, Walter Cantídio University Hospital of Ceará Federal University, Capitão Francisco Pedro Street, 1290, Ilha 6, Rodolfo Teófilo, CEP: 60430-370, Fortaleza, CE, Brazil;Department of Pathology, Walter Cantídio University Hospital of Ceará Federal University, Fortaleza, Brazil;

关键词: Oncogenic osteomalacia;    Glomangioma;    Paranasal sinus tumor;   

DOI  :  10.1186/s13256-021-02916-0

来源: Springer

【 摘 要 】

BackgroundGlomangioma is a benign tumor of mesenchymal origin, derived from the glomus body. It is responsible for the thermal regulation of the dermis. The occurrence of oncogenic osteomalacia related to glomangioma is rare. Only two cases have been reported thus far.Case presentationA 32-year-old female, Brazilian, presented diffuse pain, during pregnancy, that developed progressively, limiting her mobility. Imaging showed a femoral neck fracture, and rheumatological laboratory examination showed hypophosphatemia. Also, the patient reported episodes of epistaxis during childhood and recurrence along with progressively right nasal obstruction. Endoscopic resection of the tumor was performed, and immunohistochemistry was conclusive for glomangioma. This case report describes the third case in which endonasal endoscopic surgery resulted in a favorable outcome.ConclusionThis case of glomangioma-induced oncogenic osteomalacia suggests that surgeons and clinicians should consider sinonasal tumors as a differential diagnosis of osteomalacia, and endonasal endoscopic surgery should be a possible curative resection.

【 授权许可】

CC BY