Clinical long-term and patient-reported outcomes of dental implants in oral cancer patients

International Journal of Implant Dentistry

Vahide Cagiran¹  Wilfried Wagner¹  Keyvan Sagheb¹  Lena Katharina Müller¹  Peer W. Kämmerer¹  Lisa Theis¹  Bilal Al-Nawas¹  Eik Schiegnitz¹  Joachim Wegener² 

[1]Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany

[2]Department of Prosthodontics, University Medical Centre, Johannes Gutenberg-University, Mainz, Germany

关键词: Long-term survival;    Dental implant;    Augmented bone;    Native bone;    Irradiation;    Alveolar ridge reconstruction;    Oral cancer;   

DOI  :  10.1186/s40729-021-00373-4

来源: Springer

【 摘 要 】

Background and purposeThe aim of this clinical study was to investigate the clinical long-term and patient-reported outcome of dental implants in patients with oral cancer. In addition, analysis of the influence of radiation therapy, timing of implant insertion, and augmentation procedures on implant survival was performed.Material and methodsThis retrospective study investigated the clinical outcome of 711 dental implants in 164 oral cancer patients, inserted by experienced surgeons of the Department of Oral and Maxillofacial Surgery, University Medical Center Mainz, Germany. Oral health-related quality of life (OHRQoL) was evaluated.ResultsCumulative 5-year and 10-year implant survival rates for all included implants were 87.3% and 80.0%. Implants placed straight after ablative surgery (primary implant placement) and implants placed after completing the oncologic treatment (secondary implant placement) showed a comparable implant survival (92.5% vs. 89.5%; p = 0.635). Irradiation therapy had no significant influence on implant survival of secondary placed implants (p = 0.929). However, regarding implant site (native bone vs. augmented bone) and radiation therapy (non-irradiated bone vs. irradiated bone), implants inserted in irradiated bone that received augmentation procedures showed a statistically significant lower implant survival (p < 0.001). Patients reported a distinct improvement in OHRQoL.ConclusionsPromising long-term survival rates of dental implants in patients after treatment of oral cancer were seen. In addition, patients benefit in form of an improved OHRQoL. However, bone augmentation procedures in irradiated bone may result in an impaired implants’ prognosis.

【 授权许可】

CC BY