Long-term health-related quality of life in patients treated with subcutaneous C1-inhibitor replacement therapy for the prevention of hereditary angioedema attacks: findings from the COMPACT open-label extension study

Orphanet Journal of Rare Diseases

William R. Lumry¹  Teresa Caballero²  Subhransu Prusty³  Thomas Machnig³  John-Philip Lawo³  John Anderson⁴  Markus Magerl⁵  Bruce Zuraw⁶  Marc A. Riedl⁷  Henriette Farkas⁸  H. Henry Li⁹  Richard G. Gower^1,10  Aleena Banerji^1,11  Paul K. Keith^1,12  Michael Manning^1,13  Timothy Craig^1,14  Donald S. Levy^1,15  Hilary Longhurst^1,16  Jonathan A. Bernstein^1,17  Marco Cicardi^1,18 

[1] AARA Research Center, 10100 N. Central Expressway, Suite 100, 75231, Dallas, TX, USA;Allergy Department, Hospital La Paz Institute for Health Research (IdiPaz), Biomedical Research Network On Rare Diseases (CIBERER U754), Madrid, Spain;CSL Behring GmbH, Emil-von-Behring-Strasse 76, Marburg, Germany;Clinical Research Center of Alabama, Birmingham, AL, USA;Department of Dermatology and Allergy, Charité, Universitätsmedizin Berlin, Berlin, Germany;Department of Medicine, UC San Diego, La Jolla, CA, USA;Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA, USA;Hungarian Angioedema Reference Center, 3Rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary;Institute for Asthma and Allergy, Chevy Chase, MD, USA;Marycliff Clinical Research, Spokane, WA, USA;Massachusetts General Hospital, Boston, MA, USA;McMaster University, Hamilton, ON, USA;Medical Research of Arizona, Scottsdale, AZ, USA;Penn State University College of Medicine, Hershey, PA, USA;UC Irvine, Orange, CA, USA;University College Hospital, London, UK;Auckland District Health Board, Auckland, New Zealand;University of Cincinnati College of Medicine and Bernstein Clinical Research Center, LLC, Cincinnati, OH, USA;University of Milan, Milan, Italy;

关键词: C1-inhibitor protein;    Hereditary angioedema;    Patient-reported outcomes;    Health-related quality of life;    Productivity;    Subcutaneous;    HAEGARDA;    Anxiety;    Depression;   

DOI  :  10.1186/s13023-020-01658-4

来源: Springer

【 授权许可】

CC BY