Perinatal post-mortem magnetic resonance imaging (MRI) of the central nervous system (CNS): a pictorial review

Insights into Imaging

Olga Gómez¹  Alfons Nadal²  Núria Bargalló³  Carmen Sebastià³  Álvaro Bartolomé³  Carlos Pérez-Serrano³  Laura Oleaga⁴ 

[1] Gynecology Department, ICGON, Hospital Clínic de Barcelona, C/Villarroel no. 170, 08036, Barcelona, Spain;Pathology Department, CDB, Hospital Clínic de Barcelona, C/Villarroel no. 170, 08036, Barcelona, Spain;Radiology Department, CDIC, Hospital Clínic de Barcelona, C/Villarroel no. 170, 08036, Barcelona, Spain;Radiology Department, CDIC, Hospital Clínic de Barcelona, C/Villarroel no. 170, 08036, Barcelona, Spain;University of Barcelona, Barcelona, Spain;

关键词: Foetal magnetic resonance;    Central nervous system;    Post-mortem;    Termination of pregnancy;    Ultrasound;   

DOI  :  10.1186/s13244-021-01051-0

来源: Springer

【 摘 要 】

Central nervous system (CNS) abnormalities cause approximately 32–37.7% of terminations of pregnancy (TOP). Autopsy is currently the gold standard for assessing dead foetuses and stillborn. However, it has limitations and is sometimes subject to parental rejection. Recent studies have described post-mortem foetal magnetic resonance imaging (MRI) as an alternative and even complementary to autopsy for CNS assessment. Radiologists now play a key role in the evaluation of perinatal deaths. Assessment of foetal CNS abnormalities is difficult, and interpretation of foetal studies requires familiarisation with normal and abnormal findings in post-mortem MRI studies as well as the strengths and limitations of the imaging studies. The purpose of this pictorial review is to report our experience in the post-mortem MRI evaluation of the CNS system, including a description of the protocol used, normal CNS findings related to post-mortem status, abnormal CNS findings in our sample, and the correlation of these findings with histopathological results.

【 授权许可】

CC BY