Potential impacts of soil microbiota manipulation on secondary metabolites production in cannabis

Journal of Cannabis Research

Bulbul Ahmed¹  Mohamed Hijri² 

[1] Institut de Recherche en Biologie Végétale, Université de Montréal, 4101 Sherbrooke Est, H1X 2B2, Montréal, Québec, Canada;Institut de Recherche en Biologie Végétale, Université de Montréal, 4101 Sherbrooke Est, H1X 2B2, Montréal, Québec, Canada;African Genome Center, Mohammed VI Polytechnic University (UM6P), Lot 660, Hay Moulay Rachid, 43150, Ben Guerir, Morocco;

关键词: Cannabis;    Cannabinoid;    Cannabidiol (CBD);    Tetrahydrocannabinol (THC);    Microbiota;    Bioinoculants;   

DOI  :  10.1186/s42238-021-00082-0

来源: Springer

【 摘 要 】

BackgroundCannabis growing practices and particularly indoor cultivation conditions have a great influence on the production of cannabinoids. Plant-associated microbes may affect nutrient acquisition by the plant. However, beneficial microbes influencing cannabinoid biosynthesis remain largely unexplored and unexploited in cannabis production.ObjectiveTo summarize study outcomes on bacterial and fungal communities associated with cannabis using high-throughput sequencing technologies and to uncover microbial interactions, species diversity, and microbial network connections that potentially influence secondary metabolite production in cannabis.Materials and methodA mini review was conducted including recent publications on cannabis and their associated microbiota and secondary metabolite production.ResultsIn this review, we provide an overview of the potential role of the soil microbiome in production of cannabinoids, and discussed that manipulation of cannabis-associated microbiome obtained through soil amendment interventions of diversified microbial communities sourced from natural forest soil could potentially help producers of cannabis to improve yields of cannabinoids and enhance the balance of cannabidiol (CBD) and tetrahydrocannabinol (THC) proportions.ConclusionCannabis is one of the oldest cultivated crops in history, grown for food, fiber, and drugs for thousands of years. Extension of genetic variation in cannabis has developed into wide-ranging varieties with various complementary phenotypes and secondary metabolites. For medical or pharmaceutical purposes, the ratio of CBD to THC is key. Therefore, studying soil microbiota associated with cannabis and its potential impact on secondary metabolites production could be useful when selecting microorganisms as bioinoculant agents for enhanced organic cannabinoid production.

【 授权许可】

CC BY