Lung abscess secondary to lung cancer with a coinfection of Granulicatellaadiacens and other bacteria: a case report

BMC Infectious Diseases

Lili Xu¹  Xiaofeng Sun²  Liangliang Wu³  Xiang Huang³  Shuo Yang³  Lan Yang³  Ling Xu³ 

[1] Gansu University of traditional Chinese Medicine, Lanzhou, Gansu, China;Infection center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi city, China;The first Clinical College of Xinjiang Medical University, Urumqi city, China;

关键词: Granulicatella adiacens;    Eikenella corrodens;    Lung abscess;    Lung cancer;    Case report;   

DOI  :  10.1186/s12879-021-06191-8

来源: Springer

【 摘 要 】

BackgroundGranulicatella adiacens is facultative anaerobic Gram-positive bacteria, which mainly involve bacterial endocarditis and bacteremia, but there are few reports of local suppurative infection. A case of lung abscess with a coinfection of Granulicatella adiacens and other bacteria in a lung cancer patient will be reported in this paper. To our knowledge, this is the first case report describing lung abscess due to G.adiacens.Case presentationA 52-year-old Chinese woman was admitted to the hospital, She complained of coughing and expectoration for 1 month, shortness of breath for half a month, and dyspnea for 1 day. After a series of examinations, she was diagnosed with lung abscess, pleural effusion, and bronchogenic carcinoma. Draining pus culture demonstrated Granulicatella adiacens. After more than 5 weeks of antibiotic therapies in total, she gradually recovered to fight against lung cancer.ConclusionThis is the first reported lung abscess caused by G.adiacens. In immunosuppressed hosts, G.adiacens is a virulent pathogen associated with a spectrum of intrathoracic suppurative. Earlier diagnosis and proper drainage surgery with effective antibiotics treatment are very important, and antimicrobial treatment should be more than 5 weeks. When complex pulmonary infection interferes with the CT diagnosis, clinical suspicion of lung cancer should be increased if G.adiacens or Eikenella corrodens is detected from a pulmonary infection.

【 授权许可】

CC BY