Mesenchymal stem cell-derived exosome as a nano weapon to target the COVID-19 pandemic

Biocell

article

YASHVI SHARMA¹  SUCHI GUPTA¹  SUJATA MOHANTY¹ 

[1] Stem Cell Facility (DBT-Centre of Excellence for Stem Cell Research), All India Institute of Medical Sciences

关键词: SARS-CoV-2;    Wharton’s Jelly;    COVID-19;    Cell-free therapy;    Exosomes;    Immunomodulation;   

DOI  :  10.32604/biocell.2021.014621

学科分类：仪器

来源: Biocell

【 摘 要 】

In these times of despair when a nano-sized organism, the SARS-CoV-2, has rendered the human race helpless, made the global health status decline, and drowned the world economy, a ray of hope comes from another nano-sized particle, the exosome. The potential of mesenchymal stem cells has already been established in COVID-19; however, cell-based therapy has its risks. We thereby propose cell-free therapy using stem cells-derived exosomes to fight against COVID-19, as they can be a game-changer owing to their immunomodulatory nature, which combats the cytokine storm characterizing this disease, and their practical efficiency, which will realistically aid large access to therapy worldwide.

【 授权许可】

CC BY