Is SARS-CoV-2 responsible for relapses of Parkinson’s disease?

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

article

Scorza, Fulvio A.¹  Finsterer, Josef²  Fiorini, Ana C.³ 

[1] Universidade Federal de Sao Paulo/Escola Paulista de Medicina (UNIFESP/EPM);Messerli Institute;Programa de Estudos Pos-Graduado em Fonoaudiologia, Pontifícia Universidade Catolica de Sao Paulo (PUC-SP);Departamento de Fonoaudiologia, Escola Paulista de Medicina/Universidade Federal de Sao Paulo (EPM/UNIFESP)

关键词: SARS-CoV-2;    COVID-19;    Parkinson’s disease;    Complications;    Movement disorder;   

DOI  :  10.1186/s41983-021-00344-x

学科分类：医学（综合）

来源: Springer

【 摘 要 】

With interest, we read the article by Kamel et al. about a 56-year-old male with Parkinson’s disease (PD) in whom worsening of PD was presented as the exclusive clinical manifestation of a SARS-CoV-2 infection [1]. The study is appealing but has several limitations which raise comments and concerns. The major limitation of the study is that various causes for the deterioration of PD were not excluded. No cerebral imaging had been carried out when PD deteriorated. Mechanical ventilation is no contraindication for cerebral imaging. Missing are also a positron emission tomography (PET) study respectively a dopamin transporter (DAT) scan. No investigations of the cerebro-spinal fluid (CSF) had been carried out to exclude encephalitis or meningitis. The patient was confused on admission; thus, it is conceivable that there was mismanagement of his medication and that he had developed side effects of overdosages, such as the dopamin (DA) agonist, as he had previously experienced. We should be told for how long the patient was confused already at home and if he was responsible for the management of his daily medication alone or his caregivers.

【 授权许可】

CC BY