Can diffusion tensor imaging lesion patterns predict the outcome of ischemic stroke?

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

article

Mostafa, Mervat¹  Abdel Naseer, Maged¹  Edward, Ramy²  Edrees, Mohammad¹  Labib, Dalia M.¹ 

[1] Department of Neurology, Cairo University;Department of Radio-diagnosis, Cairo University

关键词: Diffusion tensor imaging;    Tractography;    Stroke;    Prognosis;    MRC;    NIHSS;   

DOI  :  10.1186/s41983-020-00176-1

学科分类：医学（综合）

来源: Springer

【 摘 要 】

Stroke can affect any portion of the central nervous system leading to a wide variety of symptoms depending on the part that is involved. Diffusion tensor imaging (DTI) is an emerging neuroimaging technique that allows measuring the integrity of white matter tracts. The objective of this study is to find out if the diffusion tensor tractography technique can provide prognostic information regarding clinical outcome following ischemic stroke. Forty patients with acute ischemic stroke were studied with DTI. Size of infraction, degree of reduction of fractional anisotropy (FA), and pattern of corticospinal tract (CST) affection were identified. We assessed our patients according to the National Institute of Health Stroke Scale (NIHSS) and Medical Research Council (MRC) scale at onset of stroke and 3 months later. FA reduction was correlated with MRC and NIHSS on admission (P < 0.001, 0.004 respectively) and after 3 months (P < 0.001, 0.013 respectively). The pattern of CST affection was associated with NIHSS and MRC after 3 months (P = 0.035, 0.001 respectively). DTI may be an indirect indicator of the ischemic stroke outcome.

【 授权许可】

CC BY