A hospital-based study of post-stroke aphasia: frequency, risk factors, and topographic representation

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery

article

Khedr, Eman M.¹  Abbass, Mohamed A.²  Soliman, Radwa K.³  Zaki, Ahmed F.²  Gamea, Aymen²  El-Fetoh, Noha Abo¹  Abdel-Aaal, Mahmoud A.² 

[1] Department of Neuropsychiatry, Assiut University Hospital;Department of Neuropsychiatry, South Valley University Hospital;Department of Radiology, Faculty of Medicine, Assiut University Hospital

关键词: Aphasia;    Ischemic stroke;    Hospital-based study;    Boston Diagnostic Aphasia Examination test;    National Institute of Health Stroke Scale;   

DOI  :  10.1186/s41983-019-0128-1

学科分类：医学（综合）

来源: Springer

【 摘 要 】

The crude prevalence rate of stroke in Qena, Egypt, is high (922/100,000). For the first time, we estimate the frequency of aphasia following the first-ever ischemic stroke and its relationship to the site of lesion in Arabic-speaking countries. The study was conducted on 180 acute or subacute ischemic stroke patients. Aphasia was diagnosed with the short form of the Boston Diagnostic Aphasia Examination after establishment of the cases (at least 10 days of stroke onset). Computed tomography and/or magnetic resonance imaging were performed for topographic localization of stroke, and routine laboratory investigations were done to evaluate the possible stroke risk factors. The frequency of post-stroke aphasia was recorded in 20%, and atrial fibrillation (AF) represents a high-risk factor for ischemic stroke with aphasia. The following categories were observed: global aphasia in 50%, motor aphasia in 27.7%, sensory aphasia in 11.1%, nominal aphasia in 2.8%, and conductive aphasia in 8.3%. Global aphasia was mainly associated with complete middle cerebral artery (MCA) territories infarction. Motor aphasia was associated mainly with frontal or frontoparietal operculum lesions as well as basal ganglionic lesions. Sensory aphasia was associated with temporal lobe lesions, inferior parietal lobe, and basal ganglia. Conductive aphasia showed lesions in the deep white matter of the frontal and parietal lobes. Anomic aphasia was associated with inferior parietal lobe lesion. Our data are consistent with other reports as regards the frequency and risk factors of post-stroke aphasia. Atrial fibrillation represents a high-risk factor for ischemic strokes with aphasia. Global and motor aphasia are the major subtypes. The lesion locations are predictive of aphasia subtypes.

【 授权许可】

CC BY