Mechanical thrombectomy for pulmonary embolism in patients with patent foramen Ovale

CVIR Endovascular

article

Nezami, Nariman¹  Chockalingam, Arun³  Cornman-Homonoff, Joshua¹  Marino, Angelo¹  Pollak, Jeffrey¹  Mojibian, Hamid¹ 

[1] Section of Interventional Radiology, Department of Radiology and Biomedical Imaging, Yale University School of Medicine;Division of Vascular and Interventional Radiology, Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine;Department of Radiology, Mount Auburn Hospital

关键词: Thrombectomy;    Pulmonary embolism;    Patent foramen ovale;    Anticoagulation;    Deep venous thrombosis;   

DOI  :  10.1186/s42155-020-00180-9

学科分类：计算机科学（综合）

来源: Springer

【 摘 要 】

The current level of evidence for mechanical thrombectomy (MT) of pulmonary embolism (PE) in patients with patent foramen ovale (PFO) is limited. This was a retrospective analysis of 9 patients with PFO and acute high-risk or intermediate-high-risk PE, 6 with intermediate-high risk and 3 with high-risk PE. All underwent MT using the Inari FlowTriever System from Dec 2018 to November 2019. Six of these patients had confirmed deep venous thrombosis. The technical and clinical success rate for MT in all patients was 100% and 77.8%, respectively. Right-heart strain improved in 6/8 patients on follow-up echocardiography. Mean main pulmonary artery (MPA) pressure significantly decreased after MT (p < 0.012). One patient presented with altered mental status (somnolence and disorientation) prior to coronary artery angiogram and thrombectomy, developed a middle cerebral artery embolic stroke 1 day after MT, and recovered with minor sequalae and later was discharged. There was no in-hospital mortality. MT using FlowTriever was feasible and safe, successfully improving MPA pressure in patients presenting with concurrent PFO and PE.

【 授权许可】

CC BY