Efficient eco-friendly syntheses of dithiocarbazates and thiosemicarbazones

Green Chemistry Letters and Reviews

article

Nur Halilatul Sadiqin O. Ali¹  Malai Haniti S. A. Hamid¹  Nurul Amirah ‘Aqilah Mohamad ‘Asri Putra¹  Hajar Azirah Adol¹  Aminul Huq Mirza¹  Anwar Usman¹  Tasneem A. Siddiquee²  Md. Rejaul Hoq²  Mohammad R. Karim² 

[1] Chemical Sciences, Faculty of Science, Universiti Brunei Darussalam;Department of Chemistry, Tennessee State University

关键词: Eco-friendly synthesis;    Schiff bases;    Thiosemicarbazones;    Dithiocarbazates;    Crystal structures;   

DOI  :  10.1080/17518253.2020.1737252

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

Eight Schiff bases have been synthesized by conventional and three different eco-friendly methods, whereby two aromatic carbonyl compounds viz . 2-thiophenecarboxaldehyde and salicylaldehyde were reacted with S -methyl, S -benzyl, and S - n -octyl-dithiocarbazates and thiosemicarbazide. In order to evaluate the efficiency of the synthesis methods, the time to complete the reaction and the yield of the Schiff base synthezised by eco-friendly methods, such as solvent-free grinding, water as a solvent, and lemon juice as catalyst, were compared with those synthesized by the conventional method. The chemical structures of all the synthesized Schiff bases, where two of them are novel and reported for the first time, were fully characterized by a variety of physico-chemical, analytical, and spectroscopic techniques. The molecular and crystal structures of the Schiff bases especially those having 2-thiophene moiety were further elucidated by single crystal X-ray diffraction analyzes.

【 授权许可】

CC BY|CC BY-NC