Facile synthesis of tetrazoles catalyzed by the new copper nano-catalyst

Green Chemistry Letters and Reviews

article

Vahideh Khorramabadi¹  Davood Habibi¹  Somayyeh Heydari¹ 

[1] Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University;Department of Research and Development, Faran Shimi Pharmaceutical Company

关键词: Aromatic amines;    Cu complex;    Fe 3 O 4 magnetic nanoparticles;    3-mercapto-1;    2;    4-triazole;    sodium azide;   

DOI  :  10.1080/17518253.2020.1726505

学科分类：化学（综合）

来源: Taylor & Francis

【 摘 要 】

Despite various methods for preparation of tetrazoles, they are suffering from some disadvantages such as low yield, long reaction times and harsh reaction conditions, and there are still high demands to improve the common procedures to solve problems. So, the new copper nano-catalyst was prepared by coating of the Fe 3 O 4 magnetic nanoparticles with tetraethyl orthosilicate, functionalization with 3-chloropropyltrimethoxysilane and 3-mercapto-1,2,4-triazole ligands as well as the subsequent complexation with CuCl 2 . The obtained catalyst was then characterized by different methods (ICP, XRD, EDX, SEM, TEM, TG-DTA and VSM) and applied as a heterogeneous nano-catalyst for the synthesis of diverse tetrazoles from the reaction of various aromatic amines with sodium azide and triethyl orthoformate in solvent-free condition at 100°C in good to high yields.

【 授权许可】

CC BY|CC BY-NC