A FAILED CANCER PARADIGM: implications for cancer risk assessment and patients

Journal of Cell Communication and Signaling

article

Calabrese, Edward J.¹ 

[1] Department of Environmental Health Sciences;School of Public Health and Health Sciences;University of Massachusetts

关键词: Cancer;    Precautionary principle;    Dose response;    Linear non-threshold;    Hormesis;    Risk assessment;   

DOI  :  10.1007/s12079-019-00526-6

学科分类：分子生物学，细胞生物学和基因

来源: Springer

【 摘 要 】

This commentary highlights the unique failures of environmental regulatory standards and related remedial actions to significantly reduce human cancer risks and the failure of cancer therapeutics to significantly impact cancer incidence and survival statistics despite vast resources allocated to both areas over the past half century. These dramatic institutional, scientific, medical, and regulatory failures suggest that current scientific understandings of cancer and its causation are seriously flawed and in need of a new objective re-appraisal.

【 授权许可】

CC BY