Sex-specific recombination patterns predict parent of origin for recurrent genomic disorders

BMC Medical Genomics

David J. Cutler¹  Jennifer G. Mulle²  Michael E. Zwick³  H. Richard Johnston⁴  Trenell J. Mosley⁵ 

[1] Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Whitehead Building Suite 300, 30322, Atlanta, GA, USA;Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Whitehead Building Suite 300, 30322, Atlanta, GA, USA;Department of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road NE, 30322, Atlanta, GA, USA;Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Whitehead Building Suite 300, 30322, Atlanta, GA, USA;Department of Pediatrics, Emory University School of Medicine, 2015 Uppergate Drive, 30322, Atlanta, GA, USA;Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Whitehead Building Suite 300, 30322, Atlanta, GA, USA;Emory Integrated Computational Core, Emory University, 101 Woodruff Circle, 30322, Atlanta, GA, USA;Graduate Program in Genetics and Molecular Biology, Laney Graduate School, Emory University, 201 Dowman Drive, 30322, Atlanta, GA, USA;Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Whitehead Building Suite 300, 30322, Atlanta, GA, USA;

关键词: Copy number variants;    Meiotic recombination;    Parent of origin;    3q29 deletion;   

DOI  :  10.1186/s12920-021-00999-8

来源: Springer

【 授权许可】

CC BY