Diosgenin and galactomannans, natural products in the pharmaceutical sciences

Clinical Phytoscience

Mohamad Hesam Shahrajabian¹  Wenli Sun¹  Qi Cheng²  Diorge Jonatas Marmitt³ 

[1] Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, China;Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, 100081, Beijing, China;College of Life Sciences, Hebei Agricultural University, 071000, Baoding, Hebei, China;Global Alliance of HeBAU-CLS&HeQiS for BioAl-Manufacturing, 071000, Baoding, Hebei, China;PostgraduatePorgram in Biotechnology, University of Taquari Valley- Univates, Lajeado, RS, Brazil;

关键词: Health benefits;    Diosgenin;    Galactomannans;    Natural products;   

DOI  :  10.1186/s40816-021-00288-y

来源: Springer

【 摘 要 】

BackgroundDiosgenin is an isospirostane derivative, which is a steroidal sapogenin and the product of acids or enzymes hydrolysis process of dioscin and protodioscin. Galactomannans are heteropolysaccharides composed of D-mannose and D-galactose, which are major sources of locust bean, guar, tara and fenugreek.MethodsLiterature survey was accomplished using multiple databases including PubMed, Science Direct, ISI web of knowledge and Google Scholar.ResultsFour major sources of seed galactomannans are locust bean (Ceratonia siliqua), guar (Cyamopsis tetragonoloba), tara (Caesalpinia spinosa Kuntze), and fenugreek (T.foenum-graecum). Diosgenin has effect on immune system, lipid system, inflammatory and reproductive systems, caner, metabolic process, blood system, blood glucose and calcium regulation. The most important pharmacological benefits of galactomannan are antidiabetic, antioxidant, anticancer, anticholinesterase, antiviral activities, and appropriate for dengue virus and gastric diseases.ConclusionsConsidering the importance of diosgenin and galactomannans, the obtained findings suggest potential of diosgenin and galactomannans as natural products in pharmaceutical industries.

【 授权许可】

CC BY