Medicine storage, wastage, and associated determinants among urban households: a systematic review and meta-analysis of household surveys

BMC Public Health

Alireza Mahboub-Ahari¹  Adineh Jafarzadeh²  Moslem Najafi³  Koustuv Dalal⁴  Mahmood Yousefi⁵ 

[1] Department of Health Economics, Iranian Evidence-Based Medicine Center of Excellence, Tabriz University of Medical Sciences, Tabriz, Iran;School of Management and Medical Informatics, Daneshgah Street, Daneshgah Square, Tabriz, Iran;Department of Health Economics, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran;Department of Pharmacology &Toxicology, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran;Division of Public Health Science, Institute of Health Sciences, Mid Sweden University, Sundsvall, Sweden;Department of Epidemiology, Biostatistics and EBM, Faculty of Medicine and Health Care, al-Farabi Kazakh National University, Almaty, Kazakhstan;Iranian Center of Excellence in Health Management, Department of Health Economics, School of Management and Medical Informatics, Tabriz University of Medical Sciences, Tabriz, Iran;

关键词: Medicine;    Home storage;    Wastage;    Household;    Not in use;    Expired;   

DOI  :  10.1186/s12889-021-11100-4

来源: Springer

【 摘 要 】

BackgroundIrrational household storage of medicines is a world-wide problem, which triggers medicine wastage as well as its associated harms. This study aimed to include all available evidences from literature to perform a focused examination of the prevalence and factors associated with medicine storage and wastage among urban households. This systematic review and meta-analysis mapped the existing literature on the burden, outcomes, and affective socio-economic factors of medicine storage among urban households. In addition, this study estimated pooled effect sizes for storage and wastage rates.MethodsHousehold surveys evaluating modality, size, costs, and affective factors of medicines storage at home were searched in PubMed, EMBASE, OVID, SCOPUS, ProQuest, and Google scholar databases in 2019. Random effect meta-analysis and subgroup analysis were used to pool effect sizes for medicine storage and wastage prevalence among different geographical regions.ResultsFrom the 2604 initial records, 20 studies were selected for systematic review and 16 articles were selected for meta-analysis. An overall pooled-prevalence of medicine storage and real wastage rate was 77 and 15%, respectively. In this regard, some significant differences were observed between geographical regions. Southwest Asia region had the highest storage and wastage rates. The most common classes of medicines found in households belonged to the Infective agents for systemic (17.4%) and the Nervous system (16.4%). Moreover, income, education, age, the presence of chronic illness, female gender, and insurance coverage were found to be associated with higher home storage. The most commonly used method of disposal was throwing them in the garbage.ConclusionsFactors beyond medical needs were also found to be associated with medicine storage, which urges effective strategies in the supply and demand side of the medicine consumption chain. The first necessary step to mitigate home storage is establishing an adequate legislation and strict enforcement of regulations on dispensing, prescription, and marketing of medicines. Patient’s pressure on excessive prescription, irrational storage, and use of medicines deserve efficient community-centered programs, in order to increase awareness on these issues. So, hazardous consequences of inappropriate disposal should be mitigated by different take back programs, particularly in low and middle income countries.

【 授权许可】

CC BY