Locomotive syndrome in hemodialysis patients and its association with quality of life—a cross-sectional study

Renal Replacement Therapy

Ichiei Narita¹  Suguru Yamamoto¹  Kou Kitabayashi²  Kayoko Giustini³  Isei Ei³  Yuji Ishii⁴  Yumi Katano⁴ 

[1] Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata-si, 951-8510, Niigata, Japan;Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Niigata-si, 951-8510, Niigata, Japan;Shinkohkai Murakami Kinen Hospital, 204-1 Matuyama, Murakami-si, 958-0034, Niigata, Japan;Santo-second Clinic, 1-3-25, Shichikuyama, Niigata-si, 950-0914, Niigata, Japan;Shinkohkai Murakami Kinen Hospital, 204-1 Matuyama, Murakami-si, 958-0034, Niigata, Japan;

关键词: Locomotive syndrome;    Hemodialysis;    Quality of life;    Body composition;    Physical assessment;   

DOI  :  10.1186/s41100-021-00352-w

来源: Springer

【 摘 要 】

BackgroundLocomotive syndrome (LS) is defined as impairment of mobility function.This study aimed to clarify LS and its association with quality of life in hemodialysis patients.MethodsThis is a cross-sectional study. The subjects were chronic kidney disease patients undergoing maintenance hemodialysis treatment. LS was assessed using two physical tests (two-step test, stand-up test) and one self-reported test (Geriatric Locomotive Function Scale-25). LS has two stages of severity; the beginning of the decline in mobility function is known as Locomo stage 1, and the progression of the decline of mobility function is known as Locomo stage 2. We used SF-36 to assess quality of life and examined their relationships with the Locomo stages. Chi-square test, Kruskal-Wallis test, Jonckheere-Terpstra test, and Mantel-Haenszel test were used for analysis. Multiple linear regression was used to model the cross-sectional association of Locomo stages with each component and summary score of SF-36.ResultsA total of 76 hemodialysis patients were included. The number of subjects with Locomo stage 1 and stage 2 were 19 (25%) and 53 (70%), respectively, while only four (5%) subjects did not have mobility dysfunction. Each component and summary score of the SF-36 for physical function, role emotional, physical component summary, and mental component summary were significantly associated with Locomo stages.ConclusionA high prevalence and severity of LS in hemodialysis patients was found, and the severity was associated with quality of life.

【 授权许可】

CC BY