Case report: fast reversal of malignant obesity hypoventilation syndrome after noninvasive ventilation and pulmonary rehabilitation

Sleep Science and Practice

Xu Wu¹  Liang Xie¹  Shanqun Li¹  Zilong Liu¹  Shengyu Hao¹  Lingling Pang²  Pengfei Yu² 

[1] Department of Pulmonary Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, 200032, Shanghai, China;Department of Respiratory Medicine, Yantai Yuhuangding hospital, Yantai, China;

关键词: Malignant obesity hypoventilation syndrome;    Noninvasive ventilation;    Pulmonary rehabilitation;   

DOI  :  10.1186/s41606-021-00062-6

来源: Springer

【 摘 要 】

BackgroundMalignant obesity hypoventilation syndrome (MOHS) is described as a subtype condition of OHS, characterized by extreme obesity, obese-related hypoventilation, and multiorgan dysfunction. Because of low awareness and inadequate treatment, MOHS leads to high morbidity and mortality.Case presentationA 53-year-old man was diagnosed with MOHS evidenced by extreme obesity and multiorgan abnormalities. After taken noninvasive ventilation (NIV) treatment, he was rescued. And at the end of the six-month pulmonary rehabilitation (PR) program, improvement in terms of respiratory parameters, BMI, apnea-hypopnea index (AHI), and pulmonary hypertension were observed in the patient. Two years later, the patient was still in good condition.ConclusionsThis case highlights the awareness and proper use of NIV to rescue MOHS patients. Furthermore, the benefits of PR were explored in this case, which has not been considered within the therapeutic options for MOHS patients.

【 授权许可】

CC BY