Immunologic “Cold” Squamous Cell Carcinomas of the Head and Neck Are Associated With an Unfavorable Prognosis

Frontiers in Medicine

Barbara Wollenberg¹  Karl-Ludwig Bruchhage²  Christian Idel²  Patrick Kuppler³  Luise Klapper³  Julika Ribbat-Idel³  Finn-Ole Paulsen³  Anne Offermann³  Christian Watermann³  Sven Perner⁴  Rosemarie Krupar⁵ 

[1] Department of Otorhinolaryngology, München rechts der Isar Technical University Munich, Munich, Germany;Department of Otorhinolaryngology, University of Luebeck, Luebeck, Germany;Institute of Pathology, University of Luebeck and University Hospital Schleswig-Holstein, Luebeck, Germany;Institute of Pathology, University of Luebeck and University Hospital Schleswig-Holstein, Luebeck, Germany;Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany;Pathology, Research Center Borstel, Leibniz Lung Center, Borstel, Germany;

关键词: HNSCC;    FFPE;    tumor microenvironment;    hot;    cold;    excluded;    p16;    HPV;   

DOI  :  10.3389/fmed.2021.622330

来源: Frontiers

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