Case Report: Testicular Sarcoidosis: The Diagnostic Role of Contrast-Enhanced Ultrasound and Review of the Literature

Frontiers in Medicine

Caterina Gaudiano¹  Antonio De Cinque¹  Matteo Renzulli¹  Rita Golfieri¹  Beniamino Corcioni¹  Martina Sofia Rossi²  Fulvio Colombo³  Alessandro Franceschelli³ 

[1] Department of Radiology, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;Department of Urology, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;Department of Urology, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;Andrology-Unit, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy;

关键词: andrology;    urology;    sarcoidosis;    ultrasonography;    contrast media;   

DOI  :  10.3389/fmed.2020.610384

来源: Frontiers

【 摘 要 】

Sarcoidosis is a multisystemic disease histologically characterized by non-caseating epithelioid granulomas and multinucleated giant cells; the etiology is still uncertain, and likely related to a complex interplay between environmental and genetic factors. The genitourinary system is affected in fewer than 0.2% of all clinically diagnosed cases of sarcoidosis and in 5% of those identified in autopsy studies. In this report, we describe a case of a 42–year-old male with one hypoechoic lesion per testis on B-mode evaluation; contrast-enhanced ultrasound (CEUS) on both lesions was carried out. During the early phase, the masses showed a hypovascular appearance as compared to the surrounding testicular tissue, maintaining the hypo-enhancement in the late phase. Tissue biopsy for pathological evaluation confirmed testicular sarcoid involvement, showing non-caseating granulomas. Allowing visualization of testicular microvascularisation, CEUS may play an important role in excluding malignancy, avoiding unnecessary aggressive treatment for benign conditions, such as sarcoidosis. A review of the literature of reported cases since 2004 of sarcoidosis involving the testis is also included.

【 授权许可】

CC BY