Mini-Review of Analytical Methods used in Quantification of Ellagic Acid

Reviews in analytical chemistry

article

Ojaskumar D. Agrawal¹  Yogesh A. Kulkarni¹ 

[1] Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management;Vivekanand Education Society’s College of Pharmacy, University of Mumbai

关键词: Ellagic acid;    polyphenols;    analytical methods;    extracts;    formulations;    HPLC;    HPTLC;   

DOI  :  10.1515/revac-2020-0113

学科分类：社会科学、人文和艺术（综合）

来源: De Gruyter

【 摘 要 】

Ellagic acid is an important phytochemical present in different plants such as Strawberry, Grapes, Blackberry, Raspberry etc. Chemically, ellagic acid is 2, 3, 7, 8-tetrahydroxychromeno [5, 4, 3-cde] chromene-5, 10-dione. It is an organic heterotetracyclic compound resulting from the dimerization of gallic acid molecules by oxidative aromatic coupling with intramolecular lactonization. Ellagic acid has been reported for various pharmacological activities such as anti-inflammatory, neuroprotective, cardioprotective, antioxidant, anti-mutagenic etc. Various analytical methods based on spectrophotometry, chromatography, hyphenated techniques, capillary zone electrophoresis etc. have been developed for identification and quantification of ellagic acid in natural sources and formulations. The present review provides detailed information on quantitative analysis of ellagic acid present in Strawberry, Grapes, Blackberry, Raspberry, Cranberry; Syzygium cumini seed extract, Woodfordia fruticosa plant extract, Potentilla species extracts etc. It also focuses on analytical methods for quantification of ellagic acid in herbal and traditional formulations such as Ashwagandharishta, Triphala churna, Dhatrinisha churna, Arjunarishta, Manjisthadi churna.

【 授权许可】

CC BY