Stimuli responsive nanomaterials for controlled release applications

Nanotechnology Reviews

article

Song Li¹  Wengang Li¹  Niveen M. Khashab¹ 

[1] Controlled Release and Delivery Lab (CRD), Center of Membrane and Porous Materials, King Abdullah University of Science and Technology (KAUST)

关键词: controlled release;    drug delivery;    light responsive;    magnetic nanoparticles;    nanomaterials;   

DOI  :  10.1515/ntrev-2012-0033

学科分类：社会科学、人文和艺术（综合）

来源: De Gruyter

【 摘 要 】

The controlled release of therapeutics has been one of the major challenges for scientists and engineers during the past three decades. Coupled with excellent biocompatibility profiles, various nanomaterials have showed great promise for biomedical applications. Stimuli-responsive nanomaterials guarantee the controlled release of cargo to a given location, at a specific time, and with an accurate amount. In this review, we have combined the major stimuli that are currently used to achieve the ultimate goal of controlled and targeted release by “smart” nanomaterials. The most heavily explored strategies include (1) pH, (2) enzymes, (3) redox, (4) magnetic, and (5) light-triggered release.

【 授权许可】

CC BY