Reaction of 2-thiazolidinethione with halohydrocarbon: synthesis of novel N-alkylated 2-thiazolidinethione and S-alkylated thiazoline derivatives

Heterocyclic communications

article

Yufa Liu¹  Junwei Liu¹  Xiuming Liu¹ 

[1] College of Chemistry, Chemical Engineering and Materials Science, Engineering Research Center of Pesticide and Medicine Intermediate Clean Production, Ministry of Education, Shandong Normal University

关键词: halohydrocarbon;    isomers;    2-thiazolidinethione;    thiazole derivatives;   

DOI  :  10.1515/HC.2010.015

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

Reaction of 2-thiazolidinethione with halohydrocarbon in ethanol gave a series of N -alkylated 2-thiazolidinethione and S -alkylated thiazoline derivatives in excellent yields. The reaction was carried out under mild conditions using NaOH as a base and it did not require protection from air.

【 授权许可】

CC BY|CC BY-NC-ND