A novel metal-free synthesis of 6H-isoindolo[2,1-α]indol-6-one

Heterocyclic communications

article

Chaofeng Dai¹  Alexander B. Draganov¹  Binghe Wang¹ 

[1] Department of Chemistry and Center for Biotechnology and Drug Design, Georgia State University

关键词: Beckmann rearrangement;    intramolecular cyclization;    6H-isoindolo [2;    1-a]indol-6-one;   

DOI  :  10.1515/HC.2010.007

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

6 H -Isoindolo[2,1-α]indol-6-one, a core structure for a number of biologically active compounds, was synthesized in four steps. The approach is metal-free and uses a Beckmann rearrangement followed by an intramolecular cyclization.

【 授权许可】

CC BY|CC BY-NC-ND