One-pot synthesis of fused 3,4-dihydropyrimidin-2(1H)-ones and thiones using a novel ionic liquid as an efficient and reusable catalyst: improved protocol conditions for the Biginelli-like scaffolds

Heterocyclic communications

article

Banothu Janardhan¹  Somarapu Vijaya Laxmi¹  Bavanthu Rajitha¹ 

[1] Department of Chemistry, National Institute of Technology

关键词: fused 3;    4-dihydropyrimidin-2(1H)-ones;    novel ionic liquid with multi-SO3H groups;    one-pot synthesis;    solvent free conditions;    thiones;   

DOI  :  10.1515/hc-2011-0109

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A novel ionic liquid with multi-SO 3 H groups has been found to be an efficient acid catalyst for the one-pot three-component synthesis of fused 3,4-dihydropyrimidin-2(1 H )-ones and thiones under solvent free conditions. Good yields, short reaction times, straight forward workup, reusability of the catalyst and green conditions are the most obvious advantages of this methodology.

【 授权许可】

CC BY|CC BY-NC-ND