Ionic liquid catalyzed one-pot synthesis of spiropyran derivatives via three-component reaction in water

Heterocyclic communications

article

Shuai-Shuai Jin¹  Mao-Hua Ding¹  Hong-Yun Guo¹ 

[1] College of Chemical Engineering and Materials, Zhejiang University of Technology

关键词: basic ionic liquid;    environmental friendliness;    [H3N+CH2CH2OH][CH3COO-];    one-pot;   

DOI  :  10.1515/hc-2012-0159

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

The ionic liquid [H 3 N + CH 2 CH 2 OH][CH 3 COO - ] (HEAA) catalyzes a three-component, one-pot condensation of malononitrile/ethyl cyanoacetate, 1,3-dicarbonyl compound/enol, and quinone or ninhydrin in water to afford a spiropyran derivative. This method has advantages of mild reaction conditions, short reaction time, and environmental friendliness.

【 授权许可】

CC BY|CC BY-NC-ND