Synthesis of novel 2-arylsulfonylimino-3,4- dimethyl-5-(5-S-substituted [1,3,4]oxadiazol- 2-yl)-2,3-dihydrothiazole derivatives and their plant growth stimulant activity

Heterocyclic communications

article

Karine A. Eliazyan¹  Ruzanna S. Hakobyan¹  Vergush A. Pivazyan¹  Emma A. Ghazaryan¹  Siranush V. Harutyunyan¹  Aleksandr P. Yengoyan¹ 

[1] Armenian National Agrarian University;Armenian-Russian (Slavonic) State University

关键词: 2-arylsulfonylimino-3;    4-dimethyl-2;    3-dihydrothiazole-5-carboxylic acid hydrazides;    heterocyclization;    [1;    3;    4]oxadiazol-2-yl-thiazoles;    plant growth stimulant activity;   

DOI  :  10.1515/hc-2013-0055

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

2-Arylsulfonylimino-3,4-dimethyl-2,3-dihydrothiazole-5-carboxylic acid hydrazides 2 were obtained from corresponding 2-arylsulfonylimino-4-methyl-2,3-dihydrothiazole-5-carboxylic acid ethyl esters 1 in a two-step synthesis. Heterocyclization of the hydrazide moiety yielded 2-arylsulfonylimino-3,4-dimethyl-5-(5-thioxo-4,5-dihydro-[1,3,4]oxadiazol-2-yl)-2,3-dihydro-thiazoles 3 . Treatment of compounds 3 with various alkyl halides gave corresponding S -substituted derivatives 4–6 . The plant growth stimulant activities of synthesized compounds were compared with those of similar [1,2,4]triazol- and [1,3,4,]thiadiazol-2-yl-thiazoles.

【 授权许可】

CC BY|CC BY-NC-ND