Three-component synthesis of new o-hydroxyphenyl-substituted pyrazolo[3,4-b]pyridines promoted by FeCl3

Heterocyclic communications

article

Ling Fan¹  Chaochao Yao¹  Miaomiao Shu¹ 

[1] Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University

关键词: iron(III) chloride;    pyrazolo[3;    4-b]pyridines;    three-component reaction;   

DOI  :  10.1515/hc-2015-0234

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

An efficient three-component synthesis of o -hydroxyphenyl-substituted pyrazolo[3,4- b ]pyridines from substituted salicylic aldehydes, β -keto esters and 5-aminopyrazoles in the presence of FeCl 3 is presented. Newly synthesized compounds were fully characterized by means of 1 H NMR, 13 C NMR, IR, HRMS and elemental analysis.

【 授权许可】

CC BY|CC BY-NC-ND