Synthesis and characterization of 1,3,4-thiadiazole-2,5-dithio crown ethers

Heterocyclic communications

article

Baki Çiçek¹  Zekai Onbaşıoğlu¹ 

[1] Department of Chemistry, Faculty of Science and Literature, University of Balıkesir

关键词: bismuthiol;    crown ether;    cyclization;    ion-pair extraction;    selectivity factor;   

DOI  :  10.1515/hc-2016-0097

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

Hetero-crown ethers (ligands I–IV ) containing 1,3,4-thiadiazole-2,5-dithiol (bismuthiol) were synthesized and fully characterized. The ligands were prepared by a nucleophilic substitution (S N 2) reaction of the appropriate ethylene glycol dihalide derivatives with 1,3,4-thiadiazole-2,5-dithiol dipotassium salt under highly diluted conditions, and subsequent ring closure. Complexation constants and selectivity factors for these heterocyclic ligands in dichloromethane or chloroform were determined by ion-pair extraction from an aqueous solution containing Ag + , Ca 2+ , Zn 2+ , Fe 3+ , Cr 3+ , Co 2+ , Cd 2+ , Mg 2+ , Pb 2+ , Ni 2+ , Cu 2+ , Mn 2+ , Na + and K + . These ligands could be applied as metal sensors and used to separate metals from various mixtures.

【 授权许可】

CC BY|CC BY-NC-ND