A new synthesis of pyrrolo[3,2-d]pyrimidine derivatives by a one-pot, three-component reaction in the presence of L-proline as an organocatalyst

Heterocyclic communications

article

Ramin Javahershenas¹  Jabbar Khalafy¹ 

[1] Department of Organic Chemistry, Faculty of Chemistry, Urmia University

关键词: 1;    3-Dimethyl-6-aminouracil;    4-hydroxycoumarin;    6-aminouracil;    arylglyoxals;    one-pot;    pyrrolo[3;    2-d]pyrimidines;   

DOI  :  10.1515/hc-2017-0187

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

A one-pot, three-component reaction of 4-hydroxycoumarin, arylglyoxals, and 6-aminouracil or 1,3-dimethyl-6-aminouracil in the presence of L-proline as an organocatalyst in acetic acid under reflux conditions provided a series of new pyrrolo[3,2- d ]pyrimidine derivatives in good yields.

【 授权许可】

CC BY|CC BY-NC-ND