[1,3]Thiazolo[3,2-b][1,2,4]triazol-7-ium salts: synthesis, properties and structural studies

Heterocyclic communications

article

Mikhailo Slivka¹  Nataliya Korol¹  Maksym Fizer¹  Vjacheslav Baumer³  Vasil Lendel¹ 

[1] Department of Organic Chemistry, Organic Synthesis Laboratory, Uzhhorod National University;Department of Ecology, Faculty of Humanity and Natural Sciences, University of Prešov;Department of X-ray Diffraction Studies and Quantum Chemistry, Institute for Single Crystals

关键词: functionalization;    nucleophiles;    reactivity descriptor;    regioselectivity;    [1;    3]thiazolo[3;    2-b][1;    2;    4]triazol-7-ium salts;   

DOI  :  10.1515/hc-2018-0048

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

The reactions of [1,3]thiazolo[3,2- b ][1,2,4]triazol-7-ium salts with nucleophiles were investigated. Theoretical investigation of reactivity descriptors and structural parameters of [1,3]thiazolo[3,2- b ][1,2,4]triazol-7-ium cation was carried out, and the reactivity centers of the model salts were located. An efficient general method for the synthesis of novel poly-functional derivatives of symmetric triazoles from [1,3]thiazolo[3,2- b ][1,2,4]triazol-7-ium halides was developed. The structures of the synthesized compounds were confirmed using proton nuclear magnetic resonance ( 1 H NMR), carbon-13 nuclear magnetic resonance ( 13 C NMR), Fourier-transform infrared spectroscopy (FTIR) and single-crystal X-ray analysis.

【 授权许可】

CC BY|CC BY-NC-ND