Synthesis and mass spectrometric fragmentation pattern of 6-(4-chlorophenyl)-N-aryl-4-(trichloromethyl)-4H-1,3,5-oxadiazin-2-amines

Heterocyclic communications

article

Pavlo V. Zadorozhnii¹  Vadym V. Kiselev¹  Ihor O. Pokotylo¹  Oxana V. Okhtina¹  Aleksandr V. Kharchenko¹ 

[1]Department of Organic Substances and Pharmaceutical Preparations, Ukrainian State University of Chemical Technology

关键词: 1;    3;    5-oxadiazonium cation;    FAB;    fragmentation;    4H-1;    3;    5-oxadiazine;    mass spectra;   

DOI  :  10.1515/hc-2018-0082

学科分类：内科医学

来源: De Gruyter

【 摘 要 】

The mass spectrometric fragmentation of 6-(4-chlorophenyl)- N -aryl-4-(trichloromethyl)-4 H -1,3,5-oxadiazin-2-amines was studied under fast-atom bombardment (FAB) conditions. To simplify the interpretation of the mass spectra, a number of new 4 H -1,3,5-oxadiazine derivatives containing polyisotopic elements (Cl and Br) in the arylamine substituent were synthesized. It was shown that fragmentation occurs in two main patterns.

【 授权许可】

CC BY|CC BY-NC-ND