Diisopropylamine as a single catalyst in the synthesis of aryl disulfides

Green Processing and Synthesis

article

Krzysztof Kuciński¹  Grzegorz Hreczycho¹ 

[1] Faculty of Chemistry, Adam Mickiewicz University in Poznań

关键词: amines;    base catalysis;    disulfides;    oxidative coupling;    thiols;   

DOI  :  10.1515/gps-2016-0205

来源: De Gruyter

【 摘 要 】

The search for less time-consuming and inexpensive methods for the synthesis of disulfides continues to be a hot subject of research. Herein, we report that diisopropylamine ( i Pr 2 NH) can act as a very effective catalyst for this process. The oxidative coupling of aryl thiols was carried out in the presence of catalytic amount of i Pr 2 NH in air (room temperature) in acetonitrile, without metal catalyst, additives, or external activators. This procedure opens a low-cost, green, and industrially applicable synthetic pathway to obtain aryl disulfides.

【 授权许可】

CC BY