Green synthesis of silver nanoparticles from Valeriana jatamansi shoots extract and its antimicrobial activity

Green Processing and Synthesis

article

Madiha Iqbal¹  Saud Bawazeer²  Jehan Bakht¹  Abdur Rauf³  Muhammad Raza Shah⁴  Anees Ahmed Khalil⁵  Mohamed A. El-Esawi⁶ 

[1] Department of Microbiology and Biotechnology, Abasyn University Abasyn University;Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University;Department of Chemistry, University of Swabi;Biological Sciences, HEJ Research Institute of Chemistry, University of Karachi;University Institute of Diet and Nutritional Sciences, Faculty of Allied Health Sciences, The University of Lahore;Botany Department, Faculty of Science, Tanta University

关键词: AgNPs;    Valeriana jatamansi;    antimicrobial activity;    XRD;    SEM;    FTIR;   

DOI  :  10.1515/gps-2020-0066

来源: De Gruyter

【 摘 要 】

The present study explores the potential of Valeriana jatamansi shoot extract for Ag-metal bio-reduction and its antimicrobial activity. Among the different ratios of AgNO 3 and extract tested, 1:5 (1 mL AgNO 3 and 5 mL extract) gave maximum SPR peak at 411.0 nm during UV-Vis spectrophotometric analysis, indicating the synthesis of maximum amount of AgNPs in solution. XRD analysis reported the crystalline nature of AgNPs with 13.32 nm nanocrystallite size. FTIR studies suggested the involvement of carboxylic acid (–[C–O–O–H]) and methane (–CH–) functional groups of different compounds in AgNPs reduction and fabrication. Average size of synthesized uniform shaped nanospheres was 32 nm by SEM image analysis. The produced AgNPs (1.5 mg/disc) showed growth inhibition of 71.46, 65.97, 61.5, 55.32, and 54.83% against Pseudomonas aeruginosa , Escherichia coli , Candida albicans , Xanthomonas campestris , and Staphylococcus aureus . While the least growth inhibition of 48.55% was recorded for Klebsiella pneumonia , suggesting it as the least-susceptible microbe among all the tested microbial species. P. aeruginos a was found to be most sensitive of all tested microbes, while E. coli , C. albicans , and X. campestris reported moderate susceptibility to AgNPs.

【 授权许可】

CC BY