Liraglutide Protects Nucleus Pulposus Cells Against High-Glucose Induced Apoptosis by Activating PI3K/Akt/ mTOR/Caspase-3 and PI3K/Akt/GSK3β/Caspase-3 Signaling Pathways

Frontiers in Medicine

Jing Zhang¹  Jinhui Ma²  Zhihong Li³  Yukun Li⁴  Mingyan Yao⁵  Xiaoliang Bai⁶ 

[1] Department of Cardiology, Affiliated Hospital of Hebei University, Baoding, China;Department of Endocrinology, Affiliated Hospital of Hebei University, Baoding, China;Department of Endocrinology, Baoding No.1 Central Hospital, Baoding, China;Department of Endocrinology, The Third Hospital of Hebei Medical University, Shijiazhuang, China;Department of Endocrinology, The Third Hospital of Hebei Medical University, Shijiazhuang, China;Department of Endocrinology, Baoding No.1 Central Hospital, Baoding, China;Department of Orthopedics, Baoding No.1 Central Hospital, Baoding, China;

关键词: apoptosis;    liraglutide;    nucleus pulposus cells;    signaling pathway;    diabetes mellitus;   

DOI  :  10.3389/fmed.2021.630962

来源: Frontiers

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