A Weak Response to Endoplasmic Reticulum Stress Is Associated With Postoperative Organ Failure in Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Frontiers in Medicine

Vincent Richard¹  Fabien Doguet²  Fabienne Tamion³  Benoit Veber⁴  Xavier Semaille⁴  Emmanuel Besnier⁵  Jean Selim⁵  Thomas Clavier⁵  Zoé Demailly⁵  Caroline Thill⁶ 

[1] Normandie Univ, UNIROUEN, INSERM U1096, FHU REMOD-VHF, Rouen, France;Normandie Univ, UNIROUEN, INSERM U1096, FHU REMOD-VHF, Rouen, France;Rouen University Hospital, Department of Cardiac Surgery, Rouen, France;Normandie Univ, UNIROUEN, INSERM U1096, FHU REMOD-VHF, Rouen, France;Rouen University Hospital, Department of Medical Critical Care, Rouen, France;Rouen University Hospital, Department of Anesthesiology and Critical Care, Rouen, France;Rouen University Hospital, Department of Anesthesiology and Critical Care, Rouen, France;Normandie Univ, UNIROUEN, INSERM U1096, FHU REMOD-VHF, Rouen, France;Rouen University Hospital, Department of Biostatistics, Rouen, France;

关键词: bypass;    cardiopulmonary;    cardiac surgery;    endoplasmic reticulum stress;    endothelium;    inflammation;    GRP78 protein;    human;   

DOI  :  10.3389/fmed.2020.613518

来源: Frontiers

【 授权许可】

CC BY