Age and Origin of the Founder Antithrombin Budapest 3 (p.Leu131Phe) Mutation; Its High Prevalence in the Roma Population and Its Association With Cardiovascular Diseases

Frontiers in Cardiovascular Medicine

László Balogh¹  Zoltán Mezei²  Szilvia Fiatal³  Róza Ádány⁴  Marianna Speker⁵  Tünde Miklós⁵  Zsuzsanna Szabó⁵  Zsuzsanna Bereczky⁵  Réka Gindele⁵ 

[1] Department of Cardiology and Cardiovascular Surgery, Faculty of Medicine, University of Debrecen, Debrecen, Hungary;Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary;Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary;Department of Public Health and Epidemiology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary;Magyar Tudományos Akadémia - Debrecen Public Health Research Group, University of Debrecen, Debrecen, Hungary;Division of Clinical Laboratory Science, Department of Laboratory Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary;

关键词: antithrombin deficiency;    antithrombin Budapest 3;    founder effect;    Roma population;    cardiovascular disease;    thrombosis;   

DOI  :  10.3389/fcvm.2020.617711

来源: Frontiers

【 授权许可】

CC BY