The Effects of Repeat-Dose Doxorubicin on Cardiovascular Functional Endpoints and Biomarkers in the Telemetry-Equipped Cynomolgus Monkey

Frontiers in Cardiovascular Medicine

Nancy Everds¹  Hugo M. Vargas²  James R. Turk²  Michael J. Engwall² 

[1] Non-clinical Sciences, Seattle Genetics, Inc., Seattle, WA, United States;Translational Safety and Bioanalytical Sciences, Amgen Inc., Thousand Oaks, CA, United States;

关键词: doxorubicin;    macaca fascicularis;    heart failure;    QTc interval prolongation;    echocardiography;    telemetry;    troponin;   

DOI  :  10.3389/fcvm.2021.587149

来源: Frontiers

【 授权许可】

CC BY