Twenty‐year trend of increasing obesity in young patients with poorly controlled type 2 diabetes at first diagnosis in urban Japan

Journal of Diabetes Investigation

Akifumi Kushiyama¹  Yoko Yoshida¹  Takako Kikuchi¹  Naoki Suzawa¹  Mayumi Yamamoto¹  Kentaro Tanaka¹  Mineko Okayasu¹  Tazu Tahara¹  Toshiko Takao¹  Yukiko Onishi¹ 

[1] The Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan

关键词: Body mass index;    Glycated hemoglobin;    Screening criteria;   

DOI  :  10.1111/jdi.12090

来源: Wiley

【 摘 要 】

Abstract

Aims/Introduction

To investigate trends over the past 20 years for the prevalence of obesity and glycemic control in association with a patient's first hospital visit for type 2 diabetes mellitus.

Materials and Methods

This was a historical, cross-sectional, time-series, single-center study carried out at Marunouchi Hospital. Data from type 2 diabetic patients who were never treated until their first hospital visit were analyzed for the following periods: 1986–1987 (group A, n = 453), 1996–1997 (group B, n = 547) and 2006–2008 (group C, n = 443). Data on each patient's body mass index (BMI), age, untreated duration and glycated hemoglobin levels were also collected.

Results

Obesity in younger patients (below age 40 years and ages 40–49 years in group C) with poor glycemic control increased over time. Patients with a BMI of <21.0 kg/m² or ≥23.0 kg/m² showed worse glycemic control than those with a BMI of 21.0–23.0 kg/m² in group C. Younger patients had worse glycemic control and shorter untreated durations in group C. A BMI ≥23.0 kg/m² was an independent risk factor for glycated hemoglobin levels ≥8.4% in group C, even after correction for sex, age, untreated duration and symptoms.

Conclusions

In recent years, glycemic control has worsened in young, obese patients in urban Japan. Obesity is rapidly increasing in younger patients, and patients with a BMI ≥23.0 kg/m² might be candidates for diabetes screening. This trial was registered with the University Medical Information Network Clinical Trials Registry (no. UMIN000005725).

【 授权许可】

Unknown   
© 2013 Asian Association for the Study of Diabetes and Wiley Publishing Asia Pty Ltd