Sentinel surveillance for influenza and other respiratory viruses in Côte d’Ivoire, 2003–2010

Influenza and Other Respiratory Viruses

Hervé A. Kadjo²  Euloge Ekaza²  Daouda Coulibaly⁴  Damus P. Kouassi⁴  Ndahwouh T. Nzussouo³  Bertin Kouakou²  Abdoulaye Ouattara²  Edgard V. Adjogoua²  Chantal G. Akoua&ndashKoffi²  Gilbernair A. Elia¹  Kathleen Victoir⁵  Mireille C. Bretin-Dosso² 

[1] Division vaccins, Sanofi Aventis – Pasteur, Abidjan, Côte d’Ivoire.;Respiratory virus unit, Department of epidemic virus and National Influenza Centre, Pasteur Institute, Abidjan, Côte d’Ivoire.;Influenza Division, Centers for Disease Control and Prevention, Accra, Ghana.;Institut National de l’Hygiène Publique, Service de la surveillance èpidèmiologique, Abidjan, Côte d’Ivoire.;Institut Pasteur de Paris, Direction des affaires Internationales, Paris, France.

关键词: Côte d’Ivoire;    influenza viruses;    respiratory viruses;    sentinel surveillance;   

DOI  :  10.1111/j.1750-2659.2012.00389.x

来源: Wiley

【 摘 要 】

Abstract

Background  Many countries in Africa have lacked sentinel surveillance systems for influenza and are under-represented in data used for global vaccine strain selection.

Objectives  We describe 8 years of sentinel surveillance data and the contribution of influenza and other viruses to medically attended influenza-like illness (ILI) in Côte d’Ivoire.

Methods  Sentinel surveillance was established in 2003. Nasopharyngeal (NP) specimens and epidemiologic data are collected from persons of all ages presenting with ILI at sentinel sites. Respiratory specimens have been tested for influenza using various viral and molecular diagnostic methods. A subset of 470 specimens collected from children aged 0–5 years were tested for multiple respiratory viruses using RT-PCR.

Results  From 2003 to 2010, 5074 NP specimens were collected from patients with ILI. Overall, 969/5074 (19%) of these specimens tested positive for influenza. Seasonal influenza A(H1N1) viruses predominated during 5 years and influenza A(H3N2) viruses predominated during 3 years. Influenza B viruses cocirculated with influenza A viruses during each year from 2004 to 2010. Seasonal peaks in influenza circulation were observed during the months of May, June, and October, with the largest peak corresponding with the primary rainfall season. Of 470 specimens collected from children under aged 5 who were tested for multiple respiratory viruses, a viral respiratory pathogen was detected in 401/470 (85%) of specimens. Commonly detected viruses were RSV (113 of 470 specimens, 24%), rhinoviruses (85/470, 18%), influenza (77/470, 16%), and parainfluenza (75/470, 16%).

Conclusion  In Côte d’Ivoire, there is a significant annual contribution of influenza and other respiratory viruses to medically attended ILI.

【 授权许可】

Unknown   
© 2012 Blackwell Publishing Ltd